CNNM2 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61771
Background:
Cyclin M2 is a protein in humans that is encoded by the CNNM2 gene. This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alternative Name:
Metal transporter CNNM2, Ancient conserved domain-containing protein 2, Cyclin-M2, CNNM2, ACDP2
Application Dilution: WB: 1:500~1:1000
Specificity: CNNM2 polyclonal antibody detects endogenous levels of CNNM2 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 580-630 of Human CNNM2.
MW: ~ 96 kDa
Swis Prot.: Q9H8M5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Cyclin M2 is a protein in humans that is encoded by the CNNM2 gene. This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alternative Name:
Metal transporter CNNM2, Ancient conserved domain-containing protein 2, Cyclin-M2, CNNM2, ACDP2
Application Dilution: WB: 1:500~1:1000
Specificity: CNNM2 polyclonal antibody detects endogenous levels of CNNM2 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 580-630 of Human CNNM2.
MW: ~ 96 kDa
Swis Prot.: Q9H8M5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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