CNOT7 Polyclonal Antibody

Background:
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.CNOT7 (CCR4-NOT Transcription Complex Subunit 7) is a Protein Coding gene. Among its related pathways are Deadenylation-dependent mRNA decay and Gene Expression. GO annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is CNOT8.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
BTG1 binding factor 1, BTG1-binding factor 1, CAF 1, CAF-1, CAF1, Carbon catabolite repressor protein (CCR4) associative factor 1, CCR4 associated factor 1, CCR4 NOT transcription complex subunit 7, CCR4-associated factor 1, CCR4-NOT transcription complex subunit 7, CNOT 7, Cnot7, CNOT7, hCAF 1, hCAF1

Immunogen: Fusion protein of human CNOT7

Swissprot: Q9UIV1
Gene Accession: BC007315

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.