CNP polyclonal, anti-human, mouse, sheep

Protein Family: Enzymes

Pathway and Disease: Nervous and Sensory Systems, Nucleotide Metabolism

Description:
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNPase A) is a phosphodiesterase that catalyzes the following reaction: Nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate. CNPase is present in very high levels in brain and peripheral nerve. This enzyme is found almost exclusively in oligo-dendrocytes and Schwann cells, the cells that form myelin in the central and peripheral nervous system, respectively. Therefore, CNPase has been very useful as a marker for these particular cell types.

Alternate Names: 2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, CNPase, Cnp, Cnp1

Application Notes: E: 1:500-1:1,000; WB: 1:1,000; IHC: 1:1,000

Accession No.: P13233

Antigen: Endogenous rabbit 2,3-cyclic nucleotide-3-phospho-diesterase.

Format: Each vial contains 0.1 ml of crude serum.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.