CNPase polyclonal, anti-human, mouse, rat

Background:
2',3'-cyclic nucleotide-3'-phosphodiesterase (CNPase) is a membrane-bound enzyme that can link tubulin to membranes and may regulate cytoplasmic microtubule distribution. CNPase acts as a microtubule-associated protein by promoting microtubule assembly, this activity resides in the C-terminus of the enzyme. CNPase is firmly associated with tubulin from brain tissue and thyroid cells and can be found at high concentrations in central nervous system myelin and in the outer segments of photoreceptors in the retina. Acute lead intoxication leads to disturbances in CNPase activity and the morphology of myelin.

Alternative Name:
CNP, CNPase, 2'', 2'3' cyclic nucleotide 3' phosphodiesterase, 3''-cyclic-nucleotide 3''-phosphodiesterase, CN37, CNP 1, CNP, CNP1, CNPase,

Application Dilution:
WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: CNPase polyclonal antibody detects endogenous levels of CNPase protein.

Immunogen:
recombinant protein

MW: 48 kDa

Swiss-Prot: P09543(Human) P16330(Mouse) P13233(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.