CNR1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. 

Synonyms: CB1, CNR, CB-R, CB1A, CB1R, CANN6, CB1K5

Cellular Location: Cell membrane

Immunogen:
A synthetic peptide of human CNR1

Gene Symbol: CNR1

Gene ID: 1268

Swiss prot: P21554

Calculated MW: 46/49/53kDa

Recommended dilution:
IHC 1:25-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.