COBRA1 polyclonal (Center), anti-human

COBRA1 polyclonal (Center), anti-human

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In stock
SKU
AC-AP14765c
Catalog Number: AC-AP14765c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35017
Applications: WB
Datasheet

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Background:
NELFB is a subunit of negative elongation factor (NELF),which also includes NELFA (WHSC2; MIM 606026), either NELFC orNELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF actswith DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4(SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to causetranscriptional pausing of RNA polymerase II (see MIM 180660)(Narita et al., 2003 [PubMed 12612062]).

Other Names:
Negative elongation factor B, NELF-B, Cofactor of BRCA1, NELFB, COBRA1, KIAA1182

Target/Specificity:
This COBRA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 amino acids from the Central region of human COBRA1.

Antigen Region:
256-285

Antigen Type: Synthetic Peptide

Gene Name: NELFB
Gene ID: 25920
Primary Accession: Q8WX92
NCBI Accession: NP_056271.2
Other Accession: Q8C4Y3; NP_056271.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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