Cofilin 2/CFL2 Picoband™ (clone 8C13), anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO14866
Catalog Number: AC-ABO14866
Size: 100 µg
Isotype: Mouse
Applications: WB, IHC, IF, ICC, FC
Datasheet
Request Information
Size: 100 µg
Isotype: Mouse
Applications: WB, IHC, IF, ICC, FC
Datasheet
Request Information
Description: Anti-Cofilin 2/CFL2 Antibody Picoband™ (monoclonal, 8C13) . Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
Protein Function:
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere.
Other Names: Cofilin-2, Cofilin, muscle isoform, CFL2
Clone Name(s):
Clone: 8C13
Subcellular Localization: Cytoskeleton. Nucleus matrix.
Tissue Specificity: Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Gene ID: 1073
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Cofilin 2/CFL2, identical to the related mouse sequence.
Calculated MW: 18737
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): 0
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Protein Function:
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere.
Other Names: Cofilin-2, Cofilin, muscle isoform, CFL2
Clone Name(s):
Clone: 8C13
Subcellular Localization: Cytoskeleton. Nucleus matrix.
Tissue Specificity: Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Gene ID: 1073
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Cofilin 2/CFL2, identical to the related mouse sequence.
Calculated MW: 18737
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): 0
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
| Is Featured? | No |
|---|
Write Your Own Review