Cofilin 2 (muscle) polyclonal, anti-human, mouse, rat

Background:
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

Other Names:
Cofilin-2, Cofilin, muscle isoform, CFL2

Antigen Types:
Synthetic Peptide

Gene Name:
CFL2
Gene ID:
1073
Primary Accession: Q9Y281
Other Accession: NP_619579;1073;