Cofilin2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71049
Background:
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Alternative Name:
NEM7,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: Cofilin2 polyclonal antibody detects endogenous levels of Cofilin2 protein.
Immunogen:
Recombinant protein of human CFL2.
MW: ~ 19 kDa
Swis Prot.: Q9Y281
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Alternative Name:
NEM7,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: Cofilin2 polyclonal antibody detects endogenous levels of Cofilin2 protein.
Immunogen:
Recombinant protein of human CFL2.
MW: ~ 19 kDa
Swis Prot.: Q9Y281
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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