COG2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7993
Background:
The structure and function of the Golgi apparatus is controlled by a number of multi-protein complexes that are involved in glycosylation reactions and vesicular transport. The conserved oligomeric Golgi (COG) complex consists of three subcomplexes, termed LDLC, SEC34 and GTT (Golgi transport complex), all of which contain proteins necessary for proper Golgi operation. COG2 (conserved oligomeric Golgi complex subunit 2), also known as LDLC, is a 730 amino acid component of the COG complex. Localized to the cytoplasmic side of the Golgi apparatus, COG2 is required for proper Golgi morphology and function, specifically playing a role in Golgi ribbon formation and vesicular transport. Abnormal COG2 function may cause cell death, suggesting that COG2 is an important factor in cell viability.
Alternative Name:
Brefeldin A sensitive peripheral Golgi protein, COG 2, COG complex subunit 2, COG2, COG2_HUMAN, Component of oligomeric golgi complex 2, Conserved oligomeric Golgi complex component 2, Conserved oligomeric Golgi complex subunit 2, LDLC, Low density lipoprotein receptor defect C complementing protein, Low density lipoprotein receptor defect C-complementing protein, Transcript ch4822,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: COG2 polyclonal antibody detects endogenous levels of COG2 protein.
Immunogen:
Recombinant full length Human COG2.
MW: ~ 83 kDa
Swis Prot.: Q14746
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The structure and function of the Golgi apparatus is controlled by a number of multi-protein complexes that are involved in glycosylation reactions and vesicular transport. The conserved oligomeric Golgi (COG) complex consists of three subcomplexes, termed LDLC, SEC34 and GTT (Golgi transport complex), all of which contain proteins necessary for proper Golgi operation. COG2 (conserved oligomeric Golgi complex subunit 2), also known as LDLC, is a 730 amino acid component of the COG complex. Localized to the cytoplasmic side of the Golgi apparatus, COG2 is required for proper Golgi morphology and function, specifically playing a role in Golgi ribbon formation and vesicular transport. Abnormal COG2 function may cause cell death, suggesting that COG2 is an important factor in cell viability.
Alternative Name:
Brefeldin A sensitive peripheral Golgi protein, COG 2, COG complex subunit 2, COG2, COG2_HUMAN, Component of oligomeric golgi complex 2, Conserved oligomeric Golgi complex component 2, Conserved oligomeric Golgi complex subunit 2, LDLC, Low density lipoprotein receptor defect C complementing protein, Low density lipoprotein receptor defect C-complementing protein, Transcript ch4822,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: COG2 polyclonal antibody detects endogenous levels of COG2 protein.
Immunogen:
Recombinant full length Human COG2.
MW: ~ 83 kDa
Swis Prot.: Q14746
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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