COIL polyclonal (Center), anti-human
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In stock
SKU
AC-AP14748c
Catalog Number: AC-AP14748c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34950
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34950
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.
Other Names:
Coilin, p80-coilin, COIL, CLN80
Target/Specificity:
This COIL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the Central region of human COIL.
Antigen Region:
157-186
Antigen Type: Synthetic Peptide
Gene Name: COIL
Gene ID: 8161
Primary Accession: P38432
NCBI Accession: NP_004636.1
Other Accession: NP_004636.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.
Other Names:
Coilin, p80-coilin, COIL, CLN80
Target/Specificity:
This COIL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the Central region of human COIL.
Antigen Region:
157-186
Antigen Type: Synthetic Peptide
Gene Name: COIL
Gene ID: 8161
Primary Accession: P38432
NCBI Accession: NP_004636.1
Other Accession: NP_004636.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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