Coilin polyclonal, anti-human

Background:
Coilin protein is one of the main molecular components of Cajal bodies (CBs). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. In addition to its structural role, coilin acts as glue to connect the CB to the nucleolus. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome and chromosome.

Alternative Name:
COIL, CLN80, CLN 80, CLN80, COIL, COIL, Coilin, Coilin p80, p80, P80 coilin,

Application Dilution:
WB:1:500-1:2,000
FC:1:50-1:100

Specificity: Coilin polyclonal antibody detects endogenous levels of Coilin protein.

Immunogen:
Recombinant protein

MW: 63 kDa (Predicted band size)

Swiss-Prot: P38432(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.