COL10A1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).

Alternative Name:
Collagen alpha-1(X) chain

Application Dilution: IHC: 1:100 - 1:200

Specificity: COL10A1 polyclonal antibody detects endogenous levels of COL10A1 protein.

Immunogen:
Recombinant protein of human COL10A1.

MW: ~ 66 kDa

Swis Prot.: Q03692

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.