COL18A1 polyclonal (Center), anti-human, mouse
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In stock
SKU
AC-AP10706c
Catalog Number: AC-AP10706c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22701
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22701
Applications: IHC-P, WB
Datasheet
Request Information
Background:
COL18A1 is the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure.
Other Names:
Collagen alpha-1(XVIII) chain, Endostatin, COL18A1
Target/Specificity:
This COL18A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1311-1339 amino acids from the Central region of human COL18A1.
Antigen Region:
1311-1339
Antigen Type: Synthetic Peptide
Gene Name: COL18A1 (HGNC:2195)
Gene ID: 80781
Primary Accession: P39060
NCBI Accession: NP_085059.2;NP_569712.2
Other Accession: NP_085059.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
COL18A1 is the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure.
Other Names:
Collagen alpha-1(XVIII) chain, Endostatin, COL18A1
Target/Specificity:
This COL18A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1311-1339 amino acids from the Central region of human COL18A1.
Antigen Region:
1311-1339
Antigen Type: Synthetic Peptide
Gene Name: COL18A1 (HGNC:2195)
Gene ID: 80781
Primary Accession: P39060
NCBI Accession: NP_085059.2;NP_569712.2
Other Accession: NP_085059.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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