COL19A1 (Y442) polyclonal, anti-human
€305.00
In stock
SKU
BS9133
Background:
Collagen Type XIX is an 1,142 amino acid protein encoded by the human gene COL19A1. Collagen Type XIX belongs to the fibril-associated collagens with interrupted helices (FACIT) family. Collagen Type XIX is thought to act as a cross-bridge between collagen fibrils and other extracellular matrix molecules. Collagen Type XIX is also believed to be involved in skeletal myogenesis in the developing esophagus. It may also play a role in organization of the pericellular matrix or the sphinteric smooth muscle. Collagen Type XIX is normally found as an oligomer, the subunits being disulfide-linked. Expression of Collagen Type XIX is mainly localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord.
Alternative Name:
Collagen alpha-1(XIX) chain, Collagen alpha-1(Y) chain, COL19A1
Application Dilution: IHC: 1:50~1:200
Specificity: COL19A1 (Y442) polyclonal antibody detects endogenous levels of COL19A1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 411-464of Human COL19A1.
MW: ~ 115 kDa
Swis Prot.: Q14993
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Collagen Type XIX is an 1,142 amino acid protein encoded by the human gene COL19A1. Collagen Type XIX belongs to the fibril-associated collagens with interrupted helices (FACIT) family. Collagen Type XIX is thought to act as a cross-bridge between collagen fibrils and other extracellular matrix molecules. Collagen Type XIX is also believed to be involved in skeletal myogenesis in the developing esophagus. It may also play a role in organization of the pericellular matrix or the sphinteric smooth muscle. Collagen Type XIX is normally found as an oligomer, the subunits being disulfide-linked. Expression of Collagen Type XIX is mainly localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord.
Alternative Name:
Collagen alpha-1(XIX) chain, Collagen alpha-1(Y) chain, COL19A1
Application Dilution: IHC: 1:50~1:200
Specificity: COL19A1 (Y442) polyclonal antibody detects endogenous levels of COL19A1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 411-464of Human COL19A1.
MW: ~ 115 kDa
Swis Prot.: Q14993
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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