COL1A1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14490b
Background:
This gene encodes the pro-alpha1 chains of type I collagenwhose triple helix comprises two alpha1 chains and one alpha2chain. Type I is a fibril-forming collagen found in most connectivetissues and is abundant in bone, cornea, dermis and tendon.Mutations in this gene are associated with osteogenesis imperfectatypes I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlossyndrome Classical type, Caffey Disease and idiopathicosteoporosis. Reciprocal translocations between chromosomes 17 and22, where this gene and the gene for platelet-derived growth factorbeta are located, are associated with a particular type of skintumor called dermatofibrosarcoma protuberans, resulting fromunregulated expression of the growth factor. Two transcripts,resulting from the use of alternate polyadenylation signals, havebeen identified for this gene. [provided by R. Dalgleish].
Other Names:
Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
Gene Name: COL1A1
Gene ID: 1277
Primary Accession: P02452
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes the pro-alpha1 chains of type I collagenwhose triple helix comprises two alpha1 chains and one alpha2chain. Type I is a fibril-forming collagen found in most connectivetissues and is abundant in bone, cornea, dermis and tendon.Mutations in this gene are associated with osteogenesis imperfectatypes I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlossyndrome Classical type, Caffey Disease and idiopathicosteoporosis. Reciprocal translocations between chromosomes 17 and22, where this gene and the gene for platelet-derived growth factorbeta are located, are associated with a particular type of skintumor called dermatofibrosarcoma protuberans, resulting fromunregulated expression of the growth factor. Two transcripts,resulting from the use of alternate polyadenylation signals, havebeen identified for this gene. [provided by R. Dalgleish].
Other Names:
Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
Gene Name: COL1A1
Gene ID: 1277
Primary Accession: P02452
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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