COL1A2 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP11562a
Background:
This gene encodes the pro-alpha2 chain of type I collagenwhose triple helix comprises two alpha1 chains and one alpha2chain. Type I is a fibril-forming collagen found in most connectivetissues and is abundant in bone, cornea, dermis and tendon.Mutations in this gene are associated with osteogenesis imperfectatypes I-IV, Ehlers-Danlos syndrome type VIIB, recessiveEhlers-Danlos syndrome Classical type, idiopathic osteoporosis, andatypical Marfan syndrome. Symptoms associated with mutations inthis gene, however, tend to be less severe than mutations in thegene for the alpha1 chain of type I collagen (COL1A1) reflectingthe different role of alpha2 chains in matrix integrity. Threetranscripts, resulting from the use of alternate polyadenylationsignals, have been identified for this gene. [provided by R.Dalgleish].
Other Names:
Collagen alpha-2(I) chain, Alpha-2 type I collagen, COL1A2
Gene Name: COL1A2
Gene ID: 1278
Primary Accession: P08123
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes the pro-alpha2 chain of type I collagenwhose triple helix comprises two alpha1 chains and one alpha2chain. Type I is a fibril-forming collagen found in most connectivetissues and is abundant in bone, cornea, dermis and tendon.Mutations in this gene are associated with osteogenesis imperfectatypes I-IV, Ehlers-Danlos syndrome type VIIB, recessiveEhlers-Danlos syndrome Classical type, idiopathic osteoporosis, andatypical Marfan syndrome. Symptoms associated with mutations inthis gene, however, tend to be less severe than mutations in thegene for the alpha1 chain of type I collagen (COL1A1) reflectingthe different role of alpha2 chains in matrix integrity. Threetranscripts, resulting from the use of alternate polyadenylationsignals, have been identified for this gene. [provided by R.Dalgleish].
Other Names:
Collagen alpha-2(I) chain, Alpha-2 type I collagen, COL1A2
Gene Name: COL1A2
Gene ID: 1278
Primary Accession: P08123
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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