COL2A1 polyclonal (C-term), anti-human

COL2A1 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP1418b
Catalog Number: AC-AP1418b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13830
Applications: WB
Datasheet

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Background:
Alpha-1 chain of type II collagen is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutant forms of this protein are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.

Other Names:
Collagen alpha-1(II) chain, Alpha-1 type II collagen, Collagen alpha-1(II) chain, Chondrocalcin, COL2A1

Target/Specificity:
This COL2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1209-1237 amino acids from the C-terminal region of human COL2A1.

Antigen Region:
1209-1237

Antigen Type: Synthetic Peptide

Gene Name: COL2A1 (HGNC:2200)
Gene ID: 1280
Primary Accession: P02458
NCBI Accession: NP_001835.3;NP_149162.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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