COL3A1 Monoclonal Antibody

Background:
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Research Area: Cancer, Signal Transduction, Stem Cells

Synonyms:
Alpha 1 type III collagen, Alpha1 (III) collagen, CO3A1, COL 3A1, COL3A1, Collagen alpha 1(III) chain, Collagen alpha-1(III) chain, Collagen III alpha 1 chain precursor, Collagen III alpha 1 polypeptide, Collagen type III alpha 1 (Ehlers Danlos syndrome type IV autosomal dominant), Collagen type III alpha 1, Collagen type III alpha 1 chain, Collagen type III alpha, Collagen, fetal, EDS4A, Ehlers Danlos syndrome type IV, autosomal dominant, Fetal collagen, Type III collagen

Immunogen: Synthetic Peptide

Swissprot: P02461

Calculated MW: 139 kDa
Observed MW: 138 kDa

Purification Method: Protein A purification

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-300, IF 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://www.hindawi.com/journals/bmri/2020/6093974/