COL9A1 polyclonal (Center), anti-human, mouse, rat
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In stock
SKU
AC-AP2762c
Catalog Number: AC-AP2762c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13831
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13831
Applications: IHC-P, WB
Datasheet
Request Information
Background:
COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule,and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.
Other Names:
Collagen alpha-1(IX) chain, COL9A1
Target/Specificity:
This COL9A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-456 amino acids from the Central region of human COL9A1.
Antigen Region:
428-456
Antigen Type: Synthetic Peptide
Gene Name: COL9A1
Gene ID: 1297
Primary Accession: P20849
NCBI Accession: NP_001842.3;NP_511040.2
Other Accession: Q05722
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule,and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.
Other Names:
Collagen alpha-1(IX) chain, COL9A1
Target/Specificity:
This COL9A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-456 amino acids from the Central region of human COL9A1.
Antigen Region:
428-456
Antigen Type: Synthetic Peptide
Gene Name: COL9A1
Gene ID: 1297
Primary Accession: P20849
NCBI Accession: NP_001842.3;NP_511040.2
Other Accession: Q05722
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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