COL9A3 polyclonal, anti-mouse
€388.00
In stock
SKU
BS71324
Background:
COL9A3 (also known as Collagen α3 Type IX) belongs to the fibril-associated collagens with interrupted helices (FACIT) family. COL9 is expressed in cartilage, cornea and in the vitreous portion of the eye and is a heterotrimer composed of COL9A1 and COL9A2. When expressed in hyaline cartilage, COL9 posseses a large N-terminal globular domain (NC4). Mutations in the COL9A3 gene are associated with multiple epiphyseal dysplasia (MED), a chondrodysplasia, in humans. COL9 is often co-localized with COL2A1, and may play a role in the interaction of fibrils between COL2A1 and COL9.
Alternative Name:
Collagen alpha-3(IX) chain
Application Dilution: IHC: 1:100 - 1:200
Specificity: COL9A3 polyclonal antibody detects endogenous levels of COL9A3 protein.
Immunogen:
Recombinant protein of human COL9A3.
MW: ~ 64 kDa
Swis Prot.: Q14050
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
COL9A3 (also known as Collagen α3 Type IX) belongs to the fibril-associated collagens with interrupted helices (FACIT) family. COL9 is expressed in cartilage, cornea and in the vitreous portion of the eye and is a heterotrimer composed of COL9A1 and COL9A2. When expressed in hyaline cartilage, COL9 posseses a large N-terminal globular domain (NC4). Mutations in the COL9A3 gene are associated with multiple epiphyseal dysplasia (MED), a chondrodysplasia, in humans. COL9 is often co-localized with COL2A1, and may play a role in the interaction of fibrils between COL2A1 and COL9.
Alternative Name:
Collagen alpha-3(IX) chain
Application Dilution: IHC: 1:100 - 1:200
Specificity: COL9A3 polyclonal antibody detects endogenous levels of COL9A3 protein.
Immunogen:
Recombinant protein of human COL9A3.
MW: ~ 64 kDa
Swis Prot.: Q14050
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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