Collagen I (COL1A1) Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP6107a
Background:
COL1A1 is the major component of type I collagen, and the sole component of the collagen located in cartilage. COL1A1 mutations are associated with osteogenesis imperfecta type I, II, III, and IV, Ehlers-Danlos syndrome type I and II, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a skin tumor called dermatofibrosarcoma protuberans. Two COL1A1 transcripts arise from variant polyadenylation signals for this gene.
Other Names:
Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6107a was selected from the C-term region of human COL1A1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: COL1A1
Gene ID: 1277
Primary Accession: P02452
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
COL1A1 is the major component of type I collagen, and the sole component of the collagen located in cartilage. COL1A1 mutations are associated with osteogenesis imperfecta type I, II, III, and IV, Ehlers-Danlos syndrome type I and II, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a skin tumor called dermatofibrosarcoma protuberans. Two COL1A1 transcripts arise from variant polyadenylation signals for this gene.
Other Names:
Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6107a was selected from the C-term region of human COL1A1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: COL1A1
Gene ID: 1277
Primary Accession: P02452
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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