Collagen II (8F6) Mouse mAb

Background:
Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.

Cellular localization: Secreted,extracellular space,extracellular matrix

Specificity: Human

Alternative Names:
Alpha 1 type II collagen , AOM, Col2a1 antibody

Immunogen: Synthetic Peptide

Isotype: Mouse Monoclonal IgG1

Concentration: 1mg/ml

Recommended dilutions: IHC 1:100-200

Observed band: 142kDa

GeneID: 1280

Swiss-Prot No.: P02458

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only