Collagen IV polyclonal, anti-human

Quantity: 100 µg

Background:
COL4A1, also known as ICH or Collagen alpha-1(IV), is a protein that in humans is encoded by the COL4A1 gene. It is mapped to 13q34. This gene encodes the major type IV alpha collagen chain of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. COL4A1 binds to alpha-1/beta-1 integrin and inhibits migration, proliferation, and tube formation by endothelial cells. It is also a potential therapeutic candidate for targeting tumor angiogenesis.

Description:
Rabbit IgG polyclonal antibody for Collagen alpha-1 (IV) chain (COL4A1) detection. Tested with WB, IHC-P in Human.

Synonyms:
Arresten antibody, Canstatin antibody, CO4A1_HUMAN antibody, COL4A1 antibody, COL4A1 NC1 domain antibody, COL4A2 antibody, COL4A3 antibody, COL4A4 antibody, COL4A5 antibody, Collagen Alpha 1(IV) Chain antibody, Collagen Alpha 2(IV) Chain antibody, collagen alpha-1(IV) chain antibody, Collagen IV Alpha 1 Polypeptide antibody, Collagen IV Alpha 2 Polypeptide antibody, Collagen Of Basement Membrane Alpha 1 Chain antibody, Collagen Of Basement Membrane Alpha 2 Chain antibody, Collagen Type IV Alpha 1 antibody, Collagen Type IV Alpha 2 antibody, Collagen Type IV Alpha 3 antibody, Collagen Type IV Alpha 4 antibody, Collagen Type IV Alpha 5 antibody, DKFZp686I14213 antibody, FLJ22259 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Collagen IV recombinant protein (Position: G1445-T1669). Human Collagen IV shares 97% amino acid (aa) sequence identity with mouse Collagen IV.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.