Collagen IV polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Collagen alpha-1(IV) chain is a protein that in humans is encoded by the COL4A1 gene. Type IV collagen is the major structural component of glomerular basement membranes(GBM), forming a'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in COL4A1 exons 24 and 25 are associated with HANAC(autosomal dominant hereditary angiopathy with nephropathy,aneurysms, and muscle cramps).

Description:
Rabbit IgG polyclonal antibody for Collagen alpha-1 (IV) chain (COL4A1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
Arresten antibody, Canstatin antibody, CO4A1_HUMAN antibody, COL4A1 antibody, COL4A1 NC1 domain antibody, Collagen Alpha 1(IV) Chain antibody, collagen alpha-1(IV) chain antibody, Collagen IV Alpha 1 Polypeptide antibody, Collagen Of Basement Membrane Alpha 1 Chain antibody, Collagen Type IV Alpha 1 antibody, DKFZp686I14213 antibody, FLJ22259 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Collagen IV(1654-1669aa ELRTHVSRCQVCMRRT), identical to the related rat and mouse sequence.A synthetic peptide corresponding to a sequence at the C-terminus of human Collagen IV(1654-1669aa ELRTHVSRCQVCMRRT), identical to the related rat and mouse sequence.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.