Collagen, type VII polyclonal, anti-rat

Background:
This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

Other Names:
Collagen alpha-1(VII) chain, Long-chain collagen, LC collagen, COL7A1

Antigen Types:
Synthetic Peptide

Gene Name:
COL7A1
Gene ID:
1294
Primary Accession: Q02388
Other Accession: NP_000085;1294;12836 (mouse);