COMP polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

Synonyms: MED, EDM1, EPD1, PSACH, THBS5

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human COMP

Gene Symbol: COMP

Gene ID: 1311

Swiss prot: P49747

Calculated MW: 83kDa

Recommended dilution:
WB 1:500-2000, IHC 1:10-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.