Complement factor H polyclonal, anti-human

Background:
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Other Names:
Complement factor H, H factor 1, CFH, HF, HF1, HF2

Antigen Types:
Synthetic Peptide

Gene Name:
CFH
Gene ID:
3075
Primary Accession: P08603
Other Accession: NP_000177;3075;