Connexin 25 rabbit polyclonal, anti-human, mouse, rat

Backgroud: Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008],function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Beta-type (group I) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Weakly expressed in placenta.,

Synonyms: GJB7, CX25, Gap junction beta-7 protein, Connexin-25, Cx25

Gene Name: GJB7

Gene ID: 375519

SwissProt ID: Q6PEY0

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.