Connexin-26 Polyclonal Antibody

Background:
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
connexin 26, Connexin-26, Cx26, CXB2, DFNA3, DFNB1, Gap junction beta-2 protein, GJB2, HID, KID, NSRD1, PPK

Immunogen: Synthetic peptide of human GJB2

Swissprot: P29033
Gene Accession: NP_003995

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 2.3 mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-7261/sc-130729