Connexin 30.3 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP1544a
Catalog Number: AC-AP1544a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1230
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1230
Applications: WB
Datasheet
Request Information
Background:
Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.
Other Names:
Gap junction beta-4 protein, Connexin-303, Cx303, GJB4
Target/Specificity:
This Connexin 30.3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 amino acids from the N-terminal region of human Connexin 30.3.
Antigen Region:
90-120
Antigen Type: Synthetic Peptide
Gene Name: GJB4
Gene ID: 127534
Primary Accession: Q9NTQ9
NCBI Accession: NP_694944.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.
Other Names:
Gap junction beta-4 protein, Connexin-303, Cx303, GJB4
Target/Specificity:
This Connexin 30.3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 amino acids from the N-terminal region of human Connexin 30.3.
Antigen Region:
90-120
Antigen Type: Synthetic Peptide
Gene Name: GJB4
Gene ID: 127534
Primary Accession: Q9NTQ9
NCBI Accession: NP_694944.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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