Connexin 32/GJB1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells(Bergoffen et al., 1993). For a general discussion of connexin proteins, also known as Gap junction beta-1 protein. Gap junction beta-1 protein is a protein that in humans is encoded by the GJB1 gene. In melanocytic cells GJB1 gene expression may be regulated by MITF.

Description:
Rabbit IgG polyclonal antibody for Gap junction beta-1 protein (GJB1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Charcot Marie Tooth neuropathy X linked antibody, CMTX 1 antibody, CMTX antibody, CMTX1 antibody, Connexin-32 antibody, Connexin32 antibody, CX 32 antibody, CX32 antibody, CXB1_HUMAN antibody, GAP junction 28 kDa liver protein antibody, Gap junction beta 1 protein antibody, Gap junction beta-1 protein antibody, Gap junction protein beta 1 32kD antibody, Gap junction protein beta 1 antibody, GJB 1 antibody, GJB1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Connexin 32/GJB1(215-231aa RACARRAQRRSNPPSRK), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.