Connexin 40/GJA5 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Connexin proteins oligomerize to form intercellular channels, called gap junctions, through which ions and small molecules move between adjacent cells. Connexin 40(Gap junction alpha-5 protein) is a protein that in humans is encoded by the GJA5 gene.This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.

Description:
Rabbit IgG polyclonal antibody for Gap junction alpha-5 protein (GJA5) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Connexin 40 antibody, Connexin-40 antibody, Cx40 antibody, CXA5_HUMAN antibody, Gap junction alpha 5 protein antibody, Gap junction alpha-5 protein antibody, Gap junction protein alpha 5 40kD(connexin 40) antibody, Gap junction protein alpha 5 antibody, GJA5 antibody, MGC11185 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 40/GJA5(341-358aa KRRLSKASSKARSDDLSV), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.