Connexin 43/GJA1 polyclonal, anti-human, mouse, rat

Connexin 43/GJA1 polyclonal, anti-human, mouse, rat

€455.00
In stock
SKU
AC-ABO10520
Catalog Number: AC-ABO10520
Size: 100 µg
Isotype: Rabbit IgG
Applications: WB, IHC-P, IHC-F, ICC
Datasheet
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Description: Rabbit IgG polyclonal antibody for Gap junction alpha-1 protein(GJA1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human;Mouse;Rat.Protein Name: Gap junction alpha-1 protein

Protein Function:
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). .

Other Names: Gap junction alpha-1 protein, Connexin-43, Cx43, Gap junction 43 kDa heart protein, GJA1, GJAL

Subcellular Localization: Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction . Endoplasmic reticulum .

Tissue Specificity: Expressed in the heart and fetal cochlea. .

Gene ID: 2697

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 43(351-367aa HELQPLAIVDQRPSSRA), identical to the related rat and mouse sequences.

Calculated MW: 43008

Purification: Immunogen affinity purified.

Format: Lyophilized

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
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