Connexin 43 Polyclonal Antibody

Background:
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.

Research Area: Cancer, Cardiovascular, Signal Transduction

Synonyms:
Connexin 43, Connexin-43, Cx 43, Cx43, CXA1, DFNB38, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein, Gap junction protein alpha 1 43kDa (connexin 43), Gap junction protein alpha 1 43kDa, Gap junction protein alpha like, GJA 1, Gja1, GJAL, ODD, ODDD, ODOD, SDTY3

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43

Swissprot: P17302,P23242,P08050

Calculated MW: 43 kDa
Observed MW: 43 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 0.53 mg/mL
Dilution: WB 1:1000-1:2000, IHC 1:300-1:800

Storage:
Store at -20°C. Avoid freeze / thaw cycles.