Connexin 46 rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene is a connexin and is a component of lens fiber gap junctions. Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3). [provided by RefSeq, Jan 2010],disease:Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3) [MIM:601885]. CZP3 is a form of autosomal dominant congenital cataract.,function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Alpha-type (group II) subfamily.,subunit:A connexon is composed of a hexamer of connexins. This particular connexin is a component of lens fiber gap junctions, can form both junctional and non-junctional ("hemi-") channels.,

Synonyms: GJA3, Gap junction alpha-3 protein, Connexin-46, Cx46

Gene Name: GJA3

Gene ID: 2700

SwissProt ID: Q9Y6H8

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.