Connexin 50 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP1548b
Background:
GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.
Other Names:
Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1548b was selected from the C-term region of human GJA8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GJA8
Gene ID: 2703
Primary Accession: P48165
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.
Other Names:
Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1548b was selected from the C-term region of human GJA8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GJA8
Gene ID: 2703
Primary Accession: P48165
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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