Connexin 50 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP1548a
Catalog Number: AC-AP1548a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1381
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1381
Applications: WB
Datasheet
Request Information
Background:
GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.
Other Names:
Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8
Target/Specificity:
This Connexin 50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-130 amino acids from the N-terminal region of human Connexin 50.
Antigen Region:
99-130
Antigen Type: Synthetic Peptide
Gene Name: GJA8
Gene ID: 2703
Primary Accession: P48165
NCBI Accession: NP_005258.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.
Other Names:
Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8
Target/Specificity:
This Connexin 50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-130 amino acids from the N-terminal region of human Connexin 50.
Antigen Region:
99-130
Antigen Type: Synthetic Peptide
Gene Name: GJA8
Gene ID: 2703
Primary Accession: P48165
NCBI Accession: NP_005258.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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