Contactin-2 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5672
Background:
Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
Alternative Name:
Contactin 2, Contactin2, xonal glycoprotein TAG-1, Axonin-1, Axonin 1, Axonin1, Transient axonal glycoprotein 1, TAX-1, CNTN2, AXT, TAG1, TAX1
Application Dilution: WB: 1:500~1:1000
Specificity: Contactin-2 polyclonal antibody detects endogenous levels of Contactin-2 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 157-202 of Human Contactin-2.
MW: ~ 135 kDa
Swis Prot.: Q02246
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
Alternative Name:
Contactin 2, Contactin2, xonal glycoprotein TAG-1, Axonin-1, Axonin 1, Axonin1, Transient axonal glycoprotein 1, TAX-1, CNTN2, AXT, TAG1, TAX1
Application Dilution: WB: 1:500~1:1000
Specificity: Contactin-2 polyclonal antibody detects endogenous levels of Contactin-2 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 157-202 of Human Contactin-2.
MW: ~ 135 kDa
Swis Prot.: Q02246
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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