COQ2 Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone)| a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme| which is part of the coenzyme Q10 pathway| catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency| a mitochondrial encephalomyopathy| and also COQ2 nephropathy| an inherited form of mitochondriopathy with primary renal involvement.

Research Area: Metabolism, Signal transduction, Tags & cell markers

Synonyms: COQ2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year