CORO2A Polyclonal Antibody

Background:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.

Research Area: Epigenetics and Nuclear Signaling, Signal transduction

Synonyms:
CLIPINB, COR2A, CORO 2A, CORO2A, Coronin 2A, Coronin actin binding protein 2A, Coronin like protein B, Coronin-2A, DKFZp686G19226, IR10, OTTHUMP00000021767, OTTHUMP00000021768, WD protein IR10, WD repeat containing protein 2, WD repeat protein 2, WD repeat-containing protein 2, WDR2

Immunogen: Fusion protein of human CORO2A

Swissprot: Q92828
Gene Accession: BC011690

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.54 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.