Corynebacterium Diphtheriae Toxoid (clone 11D9), anti-Cd, bacteria
€757.00
In stock
SKU
250348
Protein Family: Enzymes,Transporters
Pathway and Disease: Infectious Diseases
Description:
Corynebacterium diphtheriae is a Gram-positive, non-motile bacterium that can cause serious illness in unvaccinated humans. C. diphtheriae infects the epithelial cells of the upper respiratory tract from where they secrete a potent toxin that is absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body. The toxin is a single protein chain of 62 kDa which is "nicked" at proteolytic processing sites to produce an A chain of 21 kDa and a B chain of 40 kDa, held together by a disulfide bridge. The A-chain carries the ADP-ribosylation enzymatic activity responsible for the toxic action. This antibody reacts with diphtheria toxoid.
Alternate Names: DT, NAD(+)--dipthamide ADP-ribosyltransferase
Application Notes: Product Cat. No. 250348 reacts in ELISA wells coated with diphtheria toxoid. Product Cat. No. 250348 detects in western blot a band at approximately 63 kDa corresponding to the toxin proenzyme. Biotinylated Product Cat. No. 250347 can be used as a detection antibody in a sandwich ELISA with Product Cat. No. 250348 used as a capture antibody. E: 1:8,000; WB: 1:500
Accession No.: P00588
Antigen: Diphtheria toxoid prepared from toxin purified from C. diphtheriae subsp. intermedius Park-Williams no. 8 by formaldehyde inactivation (2), and adsorbed to aluminum hydrtoxide gel
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Infectious Diseases
Description:
Corynebacterium diphtheriae is a Gram-positive, non-motile bacterium that can cause serious illness in unvaccinated humans. C. diphtheriae infects the epithelial cells of the upper respiratory tract from where they secrete a potent toxin that is absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body. The toxin is a single protein chain of 62 kDa which is "nicked" at proteolytic processing sites to produce an A chain of 21 kDa and a B chain of 40 kDa, held together by a disulfide bridge. The A-chain carries the ADP-ribosylation enzymatic activity responsible for the toxic action. This antibody reacts with diphtheria toxoid.
Alternate Names: DT, NAD(+)--dipthamide ADP-ribosyltransferase
Application Notes: Product Cat. No. 250348 reacts in ELISA wells coated with diphtheria toxoid. Product Cat. No. 250348 detects in western blot a band at approximately 63 kDa corresponding to the toxin proenzyme. Biotinylated Product Cat. No. 250347 can be used as a detection antibody in a sandwich ELISA with Product Cat. No. 250348 used as a capture antibody. E: 1:8,000; WB: 1:500
Accession No.: P00588
Antigen: Diphtheria toxoid prepared from toxin purified from C. diphtheriae subsp. intermedius Park-Williams no. 8 by formaldehyde inactivation (2), and adsorbed to aluminum hydrtoxide gel
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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