COX-2 Monoclonal Antibody

Background:
Cox-2 is an inducible enzyme which can be involved in the cell reactions of growth factors, tumor promoters and cytokines, all of those factors can induce cox-2 overexpression. Cox-2 is also involved in the synthesis of prostaglandins. Cox-2 expression is significantly increased in 85-90% in colorectal adenocarcinoma patients, while cox-1 expression is unchanged.

Location: Cell membrane,CytoplasmP35354TBS with 0.1% Proclin300, PH7.4

Concentration: 100 μg/mL for the RTU antibody, 1mg/mL for the concentrated antibody