COX IV (clone 4D11-B3-E8), anti-human, mouse, rat, hamster, goat, monkey

Background:
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain.It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane.The complex consists of 13 mitochondrial- and nuclear-encoded subunits.The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities.The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex.This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation,and shares a promoter with it.[provided by RefSeq,Jul 2008]

Synonyms: COXIV-1, COX4, COX4-1, COXIV, COXIV-1

Cellular Location: Mitochondrion inner membrane

Immunogen:
A synthetic peptide corresponding to carboxyl terminal residues of human COX IV

Gene Symbol: COX IV

Gene ID: 1327

Swiss prot: P13073

Calculated MW: 17kDa

Recommended dilution:
WB 1:1000, ICC 1:150

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.