COX IV Mouse mAb

Background:
The enzyme cytochrome c oxidase or Complex IV, EC 1.9.3.1) is a large transmembrane protein complex found in bacteria and the mitochondrion.It is the last enzyme in the respiratory electron transport chain of mitochondria (or bacteria) located in the mitochondrial (or bacterial) membrane. It receives an electron from each of four cytochrome c molecules, and transfers them to one oxygen molecule, converting molecular oxygen to two molecules of water. In the process, it binds four protons from the inner aqueous phase to make water, and in addition translocates four protons across the membrane, helping to establish a transmembrane difference of proton electrochemical potential that the ATP synthase then uses to synthesize ATP.

Cellular localization: Membrane,Mitochondrion,Mitochondrion inner membrane

Specificity: Human

Alternative Names:
COX 4, Cox4a, COX4B, COXIV, Cytochrome c oxidase subunit 4 isoform 1 mitochondrial, MGC105470, dj857M17.2, Cytochrome c oxidase subunit IV

Immunogen: Recombinant Protein

Isotype: Mouse Monoclonal IgG1

Concentration: 1mg/ml

Recommended dilutions: WB 1:1,000-3,000, IF 1:100-200

Observed band: 15kDa

GeneID: 1327

Swiss-Prot No.: P13073

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only