COX2 Polyclonal Antibody

Background:
Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
COX 2, COX-2, COX2, Cyclooxygenase 2, Cyclooxygenase 2b, Cyclooxygenase, Cyclooxygenase-2, Cyclooxygenase2, EC 1.14.99.1, fj02a10, Glucocorticoid-regulated inflammatory cyclooxygenase, Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase, GRIPGHS, hCox 2, Macrophage activation-associated marker protein P71/73, OTTHUMP00000033524, PES-2, PGG/HS, PGH synthase 2, PGH2, PGHS 2, PGHS-2, PGHS2, PHS 2, PHS II, PHS2, Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Prostaglandin endoperoxide synthase 2, Prostaglandin G/H synthase 2, Prostaglandin G/H synthase 2 precursor, Prostaglandin G/H synthase and cyclooxygenase, Prostaglandin G/H synthase, Prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Prostaglandin-endoperoxide synthase 2, PTGS2, ptgs2a, TIS10, TIS10 protein, unp1239, wu:fj02a10

Immunogen: Synthesized peptide derived from the C-terminal region of human Cox-2

Swissprot: P35354

Calculated MW: 69 kDa
Observed MW: 80 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://www.internationaljournalofcardiology.com/article/S0167-5273(17)37240-6/abstract
https://link.springer.com/article/10.1007/s12011-018-1535-3