Cox2 Polyclonal Antibody

Background:
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction

Synonyms:
PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2, Cox2

Immunogen: Recombinant fusion protein of human Cox2 (NP_000954.1).

Swissprot: P35354
Gene ID: 5743

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.