COX4I2 antibody (clone 1F2), anti-human
€435.00
In stock
SKU
AC-AT1598a
Catalog Number: AC-AT1598a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IP, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IP, E
Request Information AC-AT1598a">Request Information
Background:
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation.
Other Names:
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial, Cytochrome c oxidase subunit IV isoform 2, COX IV-2, COX4I2, COX4L2
Antigen Type:
Recombinant Protein
Gene Name: COX4I2 (HGNC:16232)
Gene ID: 84701
NCBI Accession: NP_115998.2
Primary Accession: Q96KJ9
Other Accession: NM_032609
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation.
Other Names:
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial, Cytochrome c oxidase subunit IV isoform 2, COX IV-2, COX4I2, COX4L2
Antigen Type:
Recombinant Protein
Gene Name: COX4I2 (HGNC:16232)
Gene ID: 84701
NCBI Accession: NP_115998.2
Primary Accession: Q96KJ9
Other Accession: NM_032609
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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