COX6B1 antibody (clone 5D3), anti-human
€435.00
In stock
SKU
AC-AT1600a
Catalog Number: AC-AT1600a
Size: 50 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC
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Size: 50 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC
Request Information AC-AT1600a">Request Information
Background:
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.
Other Names:
Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1, COX6B1, COX6B
Antigen Type:
Recombinant Protein
Gene Name: COX6B1
Gene ID: 1340
NCBI Accession: NP_001854.1
Primary Accession: P14854
Other Accession: NM_001863
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.
Other Names:
Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1, COX6B1, COX6B
Antigen Type:
Recombinant Protein
Gene Name: COX6B1
Gene ID: 1340
NCBI Accession: NP_001854.1
Primary Accession: P14854
Other Accession: NM_001863
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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