COX6B1 Polyclonal Antibody

Background:
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.

Research Area: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
COX 6B, COX VIb 1, COX VIb-1, COX6B, COX6B1, COXG, COXVIb1, CX6B1, Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb, Cytochrome c oxidase subunit VIb isoform 1, cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous), Cytochrome c oxidase subunit Vib polypeptide 1

Immunogen: Recombinant protein of human COX6B1

Swissprot: P14854
Gene Accession: BC001015

Calculated MW: 10 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-103438/sc-103439